Identifyinga Researchable Problem
Identifyinga Researchable Problem
Can the use of chemotherapy (I) effectively kill the growth ofcancerous cells (O) among testicular cancer patients aged between 15and 24 years (P) compared to ill persons above 24 years (C)?
Use ofChemotherapy (I)
The use of chemotherapy in treating cancer has become a commonpractice in medical centers. The adoption of the treatment approachhowever mostly depends on preexisting studies which have proved theirefficacy. The effectiveness of chemotherapy in killing the growth ofcancerous cells among testicular cancer patients aged between 15 and24 varies with those who are above 24 years.
Crawford 2013 indicates that the application of chemotherapy has beeneffective in childhood as attested by the satisfactory resultswitnessed among children who have acute lymphoblastic leukemia. Theauthor suggests that the success of the approach has formed the basisfor the development of chemotherapeutic drugs in older patients. Theresults could be an indication of the effectiveness of the use ofchemotherapy among younger patients aged 15 to 24 years.
Kim (2015) postulates that the efficacy of chemotherapy in treatingcancers does not differ remarkably among the different age groups. Ina study conducted that focused on evaluating the effectiveness ofchemotherapy in treating colorectal cancer among the elderly,findings indicated that there was no significant variation.
Sanoff et al. (2012) indicate that the application of chemotherapyamong elderly patients is effective in dealing with cancerous cells.The study which focused on cancerous patients aged 75, and aboveshowed remarkable beneficial effects.
Lipshultz et al. (2014) state that the use of chemotherapy in thetreatment of cancers has been associated with cardiotoxicity amongthe younger generation. Despite the success associated with thedrugs, children have been affected negating the need for closemonitoring.
Hamlin et al. (2014) acknowledge the effectiveness of chemotherapyespecially among the elderly. The results could guide the nursepractitioners in helping determine the best treatment for cancerpatients in the identified age groups.
The study focuses on understanding the impact of chemotherapy on theproliferation of cancerous cells among the selected age groups.
The populations being investigated are patients aged 15 to 24 yearsand those above twenty-four.
Crawford, S. (2013). Is it time for a new paradigm for systemiccancer treatment? Lessons from a century of cancer chemotherapy.Frontiers in Pharmacology, 4, 68.http://doi.org/10.3389/fphar.2013.00068
Hamlin, P. A., Satram-Hoang, S., Reyes, C., Hoang, K. Q., Guduru, S.R., & Skettino, S. (2014). Treatment Patterns and ComparativeEffectiveness in Elderly Diffuse Large B-Cell Lymphoma Patients: ASurveillance, Epidemiology, and End Results-Medicare Analysis. TheOncologist, 19(12), 1249–1257.http://doi.org/10.1634/theoncologist.2014-0113
Kim, J. H. (2015). Chemotherapy for colorectal cancer in the elderly.World Journal of Gastroenterology : WJG, 21(17),5158–5166. http://doi.org/10.3748/wjg.v21.i17.5158
Lipshultz, S. E., Diamond, M. B., Franco, V. I., Aggarwal, S., Leger,K., Santos, M. V., … Chow, E. J. (2014). ManagingChemotherapy-Related Cardiotoxicity in Survivors of ChildhoodCancers. Paediatric Drugs, 16(5), 373–389.http://doi.org/10.1007/s40272-014-0085-1
Sanoff, H. K., Carpenter, W. R., Stürmer, T., Goldberg, R. M.,Martin, C. F., Fine, J. P., … Schrag, D. (2012). Effect of AdjuvantChemotherapy on Survival of Patients With Stage III Colon CancerDiagnosed After Age 75 Years. Journal of Clinical Oncology,30(21), 2624–2634. http://doi.org/10.1200/JCO.2011.41.1140