Calcium plays a critical role when it comes to bone formation andcell signaling pathways. The deficiency of the mineral ion will havesignificant effects on the process of formation of bones. The roleplayed by calcium in the organ system is imparting strength to thebones and teeth. A deficiency will have adverse effects on theskeletal system that encompasses the bones. The effect will bemanifested with deformities in the process of bone formation.
The effect of calcium deficiency at the cellular level is exhibitedin abnormality in the cell signaling process. Calcium plays acritical role in facilitating the process of signaling. The impairedcommunication between cells can be detrimental to the body. Thedeficiency can equally affect the nerve cells. Through the same,communication will be significantly affected. The heart organ canalso be affected by calcium deficiency, and this can be manifestedwhen the heart skips a beat or stops beating. Further, the musclesare affected especially since contraction is impaired.
The symptoms of calcium deficiency vary significantly. It can rangefrom mild to severe to life-threatening state. If the condition ischronic, notable symptoms include the development of rickets,osteoporosis, and osteopenia. Further, the symptoms can includenumbness and a feeling of tingling sensation in the fingers and toes.In extreme cases, heart failure can be noticed especially because ofthe effect the mineral ion has on the heart organ. Those affected canequally experience chest pain. Further, calcium deficiency can resultin muscle cramps particularly at the back and the legs.
Calcium equilibrium is maintained through the existence of channelsand pumps that determine the flow of calcium ions in theextracellular fluid and inside the cells. The calcium ions can alsobe removed from the calcium-binding proteins to increase theirconcentration.