Anatomyand Physiology- T-tubules
Atraverse tubule (T-tubule) is a deep invagination found within thesarcolemma. Sarcolemma refers to the plasma membrane, both of thecardiac and skeletal muscle cells. They surround the sarcoplasmicreticulum sheaths, and they are further fragmented into myoglobin andthe mitochondrion. As they create invaginations, the t-tubules giveroom for permeation of impulses within the cell membrane. Thisprocess activates and ultimately excites the sarcoplasmic reticulum.Ones activated, the sarcoplasmic reticulum reacts by creating anetwork around the delicate myofibrils that are responsible for thestorage and releasing of essential calcium supplies that are used inthe contraction of the muscles. The t-tubules play a pivotal role inthe transmission and reception of data in the course of directing theelectrical impulses. In the receiving part, they make it possible forcalcium to be infiltrated in the L-type Calcium Channels. Thechannels after absorbing calcium, they transmit it to thecalcium-release channels that enable the skeletal muscles tocontract.
Severalimpacts may be felt by a person having malfunctioning T-tubules.First, the contractions of the muscles will be prolonged. Thiscondition is common in the leg muscles, hands and the face. In theearly stages, the person may experience breathing complications,muzzling, movements that are stiff that are likely to improve afterbeing repeated and falling frequently. Furthermore, the person canface difficulties in opening their eyelids after vigorouscontractions.
Thereare also several complications attributed to this condition. One maysuffer injuries due to falling, weaknesses in the abdominal muscles,and prolonged complications in the joints. Besides, due to theswallowing difficulties, one is likely to suffer from aspirationpneumonia and recurrent choking. Gagging complications are alsocommon among infants.