ANATOMY AND PHYSIOLOGY – ENZYMES 5
Anatomy andPhysiology – Enzymes
Anatomy andPhysiology – Enzymes
Osteoblasts are types of cells which are found in a human being. Thecells are made up of a single nucleus. The primary function of thecells in a human is to synthesize bones. However, during theformation of cells in a human being, the cells work in groups. Notethat they only function when they are in groups of many cells whichare connected. The maintenance of bones can thus be said to be adelicate business which should be taken seriously by human beings. Inthis case, we will consider a situation where the enzyme responsiblefor the development and functioning of osteoblasts in a person isantagonized by a compound found in a common pesticide. This paperwill compare symptoms which occur in people at various agestructures. It will also discussand relate them to the function in specific organs and organ systems.
Effects of Blocking Enzymes Which Produce Osteoblasts in a HumanBeing
There are various common signs and symptoms of blocking functioningof osteoblasts which are experienced in all the stages of life.However, to the infants, the common symptom is a bone fracture whichoccurs more quickly than it can be expected. In fact, this is themain symptom which is mainly experienced in the infants (Langton& Njeh, 2016). For example, a little mishandling ofa small kid may lead to a bone fracture, common cases of bonefracture occur when for example lifting the child when holding her orhim by using his or her hands. However, the other symptom in aninfant is a stooped posture which the baby assumes while growing.
To an adolescent, the common symptom which is commonly experienced isthe loss of height which occurs time over time. For example, the lossof height can be experienced after a few months. Instead of anincrease of height, it decreases, and this is contrary to what shouldhappen because the individual should be growing (Langton& Njeh, 2016). However, the other symptoms whichare likely to be experienced at this stage include a back pain andalso unexpected bone fracture.
In adults, the main symptom which is experienced is a stoopedposture. However, it is mainly suffered because of a severe backpain. The back pains are experienced because of a collapsed vertebra.For example, at various times you will hear an adult complaining ofback pain from time to time. The other experienced symptoms are theloss of height and maybe unexpected bone fractures.
On the other hand, in the old stage of life, the blockage ofosteoblasts is mainly experienced when a person complains of backpain. Back grief and unexpected fractures are the main symptoms whichare experienced by the old people. For example, a slight topple ofan old man will lead to a bone fracture in an arm or a leg. The sameparticular individual will also keep on complaining about a severeback pains times and again. The other symptom in this stage may be astooped posture.
The bony skeleton is an important body organ which has severalfunctions in a human being. The bony skeleton serves all the basicfunctions which include the provision of mobility, providing supportand protecting the entire body. However, it also has the roles of thereservoir function which works as the store of the essential minerals(Langton &Njeh, 2016). For example, during the childhood and theadolescent stage, the bones are sculpted through a process known asmodeling. It a process which allows new bones to be formed at onesite and the removal of the old bones from another location. Theprocess occurs within the same particular bone. It is a processwhich allows the bones to shift regarding space and also the bones togrow.
Fig (I) and (II) above explain the processes of modeling andremodeling
All of the above-discussed symptoms are attributed to the hinderingof the processes of both modeling and remodeling. However, thesequence of resorption, reversal, activation and formation of thebones depend on various cells which are of the osteoblast lineage.They are concentrated on the surface or in the inside of the bonemarrows. They act on the blood cells precursors which lead to theformation of the borne-resorbing osteoclasts. Affecting the functionsof osteoblasts leads to the symptoms discussed.
Langton, C.M., & Njeh, C. F. (Eds.). (2016). Thephysical measurement of bone.CRC Press.